Semax 5mg
$48.00
Semax 5mg is a high-purity synthetic analog of the adrenocorticotropic hormone (ACTH) fragment 4-10. This heptapeptide (Met-Glu-His-Phe-Arg-Trp-Gly) is specifically synthesized for advanced laboratory research into neuroprotection, cognitive enhancement signaling, and brain-derived neurotrophic factor (BDNF) expression.
| Property | Specification |
|---|---|
| Compound Name | Semax |
| CAS Number | 80714-61-0 |
| Vial Concentration | 5mg single compound |
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| Parent Fragment | ACTH(4-7) + C-terminal Pro-Gly-Pro stabilizing tail |
| Molecular Formula | C₃₇H₅₁N₉O₁₀S |
| Molecular Weight | ~813.9 g/mol |
| Class | Synthetic heptapeptide (nootropic / neuroprotective) |
| Key Property | Crosses the blood-brain barrier; no adrenal steroidogenesis |
| Purity Rating | >99% (HPLC & MS verified) |
| Format | White lyophilized powder |
| Storage | -20°C, protected from light and moisture |
Semax 5mg peptide for Sale | 99% Pure ACTH-Derived Nootropic Peptide (Precision Format)
Semax 5mg is the precision-format version of the ACTH-derived neuropeptide that’s become a cornerstone of neuroprotection and cognitive-signaling research. It’s a synthetic heptapeptide engineered to deliver ACTH’s brain effects — boosting the nervous system’s own growth factors like BDNF — while completely skipping the hormonal side effects of the parent hormone (Peptpedia, 2026). Verified 99%+ pure and lyophilized, the 5mg vial is the right-sized quantity for dose-response, titration, and focused single-condition studies.
A quick, honest word before we go further: getting Semax to perform in the lab is almost entirely about handling. It’s a small peptide, and small peptides reward careful reconstitution and storage — or punish sloppiness with degraded, unreliable results. So this page leans into exactly that: the practical, step-by-step how-to that keeps your material intact and your data clean. Let’s get into it.
Scope note: research-grade material for in-vitro and laboratory research by qualified professionals only. Not approved by the FDA or EMA (approved in Russia/Ukraine), not for human or veterinary use, and nothing here is a dosing protocol.

What Semax 5mg Is (In Brief)
Semax is a synthetic heptapeptide derived from the ACTH(4-7) fragment, stabilized with a C-terminal Pro-Gly-Pro tail so it resists enzymatic breakdown (Peptidepedia, 2026). Its correct sequence is Met-Glu-His-Phe-Pro-Gly-Pro. Researchers study it for BDNF and NGF upregulation, neuroprotection against oxidative and hypoxic stress, cognitive-signaling (dopamine/serotonin) modulation, and ischemic-stroke recovery models — and it crosses the blood-brain barrier, unlike many peptides its size.
Now to the part that actually determines whether your research works: handling it properly.
How to Reconstitute Semax 5mg — Full Step-by-Step
Reconstitution is where most peptide problems begin. Follow these steps and your Semax 5mg dissolves cleanly, at known concentration, without degradation.
| Step | What to Do | Why It Matters |
|---|---|---|
| 1. Gather materials | Bacteriostatic water (or sterile water), alcohol wipes, a sterile syringe, and your vial | Bacteriostatic water resists microbial growth for multi-use vials |
| 2. Warm the vial | Let the sealed vial reach room temperature | Cold glass causes condensation that skews concentration |
| 3. Sanitize | Wipe both vial stoppers with an alcohol swab | Prevents contamination of a multi-draw vial |
| 4. Draw your solvent | Pull your chosen volume into the syringe (see the concentration guide below) | Volume sets your working concentration |
| 5. Add slowly, down the wall | Angle the needle so liquid runs down the inner glass wall — never jet it onto the powder | Direct impact shears the peptide and denatures it |
| 6. Dissolve gently | Swirl or roll the vial; do not shake | Shaking foams and fractures peptide bonds |
| 7. Rest | Let it sit a minute until fully clear | Confirms complete dissolution before use |
| 8. Aliquot | Split into single-use portions | Protects the batch from repeated freeze-thaw |
How to Choose Your Reconstitution Volume
The amount of solvent you add sets your concentration. Here’s a simple guide for a 5mg vial — pick the volume that suits your protocol’s precision.
| Solvent Added | Resulting Concentration | Best For |
|---|---|---|
| 1 mL | 5 mg/mL (high concentration) | Small working volumes, minimal draw error |
| 2 mL | 2.5 mg/mL | A balanced middle ground |
| 5 mL | 1 mg/mL (easy math) | Fine titration and dose-response precision |
Tip: for dose-response work, a lower concentration (more solvent) gives you finer control over each measured draw — which is exactly why the 5mg precision format pairs well with a 5 mL reconstitution.
How to Store Semax 5mg for Maximum Shelf Life
Storage is the other half of the reliability equation. Handle it right and lyophilized Semax stays stable for a long time.
- Before reconstitution (powder): store sealed at -20°C, kept dark and dry. In this state it’s stable long-term — this is how you’d hold stock between studies.
- After reconstitution (solution): move to 2–8°C (standard refrigeration), protect from light, and use within a few weeks.
- Never repeatedly freeze-thaw a reconstituted solution — each cycle degrades it. This is exactly why step 8 above says aliquot first.
- Keep it dark: light accelerates peptide breakdown, so amber vials or a shielded container help.
How to Handle Semax Safely in the Lab
Good lab practice protects both your material and you.
- Work clean: sanitize surfaces and wear gloves; you’re handling a research chemical, not a consumer product.
- Label everything: note the compound, concentration, and reconstitution date on each aliquot — future-you will thank present-you.
- Inspect before every use: a proper Semax solution is clear and colorless. Cloudy, particulate, or discolored means it’s compromised — discard it.
- Follow your institution’s protocols for research-chemical handling and disposal.
Where Semax 5mg Fits in Research
| Research Focus | What’s Being Investigated |
|---|---|
| BDNF & NGF Expression | Neurotrophic-factor upregulation in brain-tissue models |
| Neuroprotective Mechanisms | Mitigation of oxidative and hypoxic neuronal damage |
| Cognitive Signaling | Dopamine/serotonin modulation in focus and learning models |
| Ischemic Stroke Research | Neurological recovery following vascular events |
| Dose-Response Modeling | Precise titration enabled by the 5mg format |
Expanded Technical Specifications
Accuracy note: these are the specs for genuine Semax (the ACTH(4-7) + Pro-Gly-Pro analog). The sequence Met-Glu-His-Phe-Arg-Trp-Gly is the un-modified ACTH(4-10) fragment — a different molecule. Always confirm identity against your COA.
| Property | Specification |
|---|---|
| Compound Name | Semax |
| CAS Number | 80714-61-0 |
| Vial Concentration | 5mg single compound |
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| Parent Fragment | ACTH(4-7) + C-terminal Pro-Gly-Pro stabilizing tail |
| Molecular Formula | C₃₇H₅₁N₉O₁₀S |
| Molecular Weight | ~813.9 g/mol |
| Class | Synthetic heptapeptide (nootropic / neuroprotective) |
| Key Property | Crosses the blood-brain barrier; no adrenal steroidogenesis |
| Purity Rating | >99% (HPLC & MS verified) |
| Format | White lyophilized powder |
| Storage | -20°C, protected from light and moisture |
The GLP1 Peptides Quality Standard
| Standard | What You Get |
|---|---|
| Verified 99%+ Purity | Every batch confirmed by HPLC and Mass Spectrometry |
| Advanced Lyophilization | Freeze-drying that protects the 7-residue chain from degradation |
| Analytical Transparency | A batch-specific Certificate of Analysis (COA) with every order |
| Synthesis Precision | Exact sequencing for a consistent research analog |
For precise dose-response work, that COA is what makes your reconstitution math trustworthy — it confirms both purity and the correct Met-Glu-His-Phe-Pro-Gly-Pro identity.
Semax vs Selank
| Compound | Origin | Primary Action | Note |
|---|---|---|---|
| Semax (this product) | ACTH(4-7) fragment | Cognition-first, neuroprotective | Dual BDNF/NGF; blood-brain-barrier penetrant |
| Selank | Tuftsin (IgG fragment) | Anxiety-first, cognitive support | Anxiolytic without sedation |
The clean framing: Semax and Selank came from the same Russian institute and are often studied as a pair — Semax leads on cognition and neuroprotection, Selank on anxiety. Many research designs use them side by side.
Semax 5mg for Sale — Shipping Worldwide
Our research-grade Semax 5mg ships as HPLC/MS-verified, COA-backed lyophilized vials, sealed and bench-ready. We fulfill orders for laboratories and independent researchers across the highest-demand markets:
- 🇺🇸 USA — fast domestic dispatch
- 🇨🇦 Canada — reliable cross-border delivery
- 🇩🇪 Germany (Deutschland) — trusted EU logistics
- 🇫🇷 France — secure European shipping
Deciding to buy Semax 5mg? It’s the precision pick — a verified, right-sized quantity for dose-response and focused neuropeptide research, backed by documentation you can trust.
FAQs about Semax 5mg
1. What is Semax 5mg? A precision 5mg vial of Semax, a synthetic ACTH(4-7)-derived heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro), supplied as a lyophilized powder for neuroprotection and cognitive-signaling research.
2. How do I reconstitute Semax 5mg? Warm the vial, sanitize the stopper, add bacteriostatic or sterile water slowly down the inner glass wall, swirl gently (never shake), let it clear, then aliquot. The full step-by-step is in the how-to table above.
3. How much water should I add? It depends on your target concentration — 1 mL gives 5 mg/mL, 5 mL gives 1 mg/mL (easy math for titration). See the reconstitution-volume guide above.
4. How should Semax 5mg be stored? Lyophilized powder at -20°C, sealed and dark; reconstituted solution at 2–8°C, protected from light, with freeze-thaw cycles avoided.
5. How long does reconstituted Semax last? Kept cold, dark, and refrigerated at 2–8°C, use it within a few weeks — and never refreeze it. Aliquoting at reconstitution is the way to preserve the rest.
6. Why shouldn’t I shake the vial? Shaking foams the solution and shears the peptide’s molecular bonds, degrading it. Gentle swirling dissolves it without damage.
7. Isn’t the Semax sequence Met-Glu-His-Phe-Arg-Trp-Gly? No — that’s the un-modified ACTH(4-10) fragment. Genuine Semax is Met-Glu-His-Phe-Pro-Gly-Pro. They’re easily confused, so verify identity on the COA.
8. Why choose the 5mg over the 10mg? The 5mg is the precision format — ideal for dose-response, titration, and focused single-condition studies. Step up to 10mg for longer or high-frequency work.
9. Does Semax cause hormonal effects like ACTH? No — it’s engineered to keep ACTH’s neuro effects without stimulating adrenal steroidogenesis, so there’s no cortisol cascade.
10. Is Semax FDA approved? No — approved in Russia and Ukraine for stroke and cognitive disorders, but not by the FDA or EMA. This material is for laboratory research only.
11. What solvent is best for reconstitution? Bacteriostatic water is ideal for multi-use vials (it resists microbial growth); sterile water works for single-use preparation.
12. Where can I buy Semax 5mg internationally? GLP1 Peptides ships research-grade, COA-verified Semax 5mg to the USA, Canada, Germany, and France in sealed lyophilized vials. See the shipping section above.







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