Melanotan 1 10mg | Buy 99% Pure MC1R-Selective α-MSH Analog (Afamelanotide)

Pigmentation research lives and dies on one thing: knowing exactly what your peptide is doing at exactly which receptor. Use a compound that fires across every melanocortin receptor and your melanogenesis data gets tangled up with appetite, cardiovascular, and CNS signals. That’s why the Melanotan 1 10mg vial has become a melanocortin-lab staple — it’s a clean, MC1R-selective tool with a linear structure that stays close to native α-MSH, giving you pigment signaling without the noise.

And it carries a distinction almost no research peptide can claim: as afamelanotide (brand Scenesse), this exact molecule is an approved pharmaceutical for a rare light-sensitivity disorder. The research-grade Melanotan 1 you’ll find here is that same peptide, supplied as a lyophilized powder for the lab. This 10mg format gives you a precise, standard research quantity — enough for defined melanogenesis and photoprotection studies. Here’s the full rundown.

Scope note: research-grade material for in-vitro and laboratory use by qualified professionals only. This powder is not the approved drug (Scenesse), and is not intended for human, cosmetic, or veterinary use.

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Setting the Record Straight: MT-1 Is MC1R-Selective

Let’s tackle the most common mislabeling head-on, because it changes how you’d design a study. Melanotan 1 is an MC1R-selective agonist — it acts primarily on the melanocortin-1 receptor on melanocytes, with minimal activity at MC3R, MC4R, and MC5R.

You’ll sometimes see MT-1 described as a “non-selective” agonist hitting all four melanocortin receptors. That’s not accurate — that broad profile belongs to Melanotan II, the cyclic derivative. MT-1’s linear 13-amino-acid structure, closely resembling endogenous α-MSH, is exactly what keeps it targeted. For researchers, that selectivity is the whole appeal: you can study pigmentation pathways without MC4R-driven systemic effects muddying the results.

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Same Molecule as an Approved Drug — Here’s Why That’s Useful

Most research peptides have thin human data. Melanotan 1 is the exception. It’s chemically identical to afamelanotide, which reached the market as Scenesse — FDA-approved in 2019 and EMA-approved in 2014 — for erythropoietic protoporphyria (EPP), a rare disorder causing severe pain from light exposure

Why should a researcher care? Because that approval came with genuine Phase 3 pharmacology, safety, and mechanism data — a validated foundation that most research compounds simply don’t have. Two honest caveats, though: the approval covers the EPP indication only (there’s no cosmetic or tanning approval), and the approved product is a controlled-release implant, not the research powder. Same molecule, entirely different regulatory context.

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How Melanotan 1 Drives Pigment

The mechanism is worth a moment. When Melanotan 1 binds MC1R on melanocytes, it stimulates production of eumelanin — the brown-black pigment that absorbs UV radiation and mops up free radicals. That’s the protective one. It contrasts with pheomelanin, the reddish pigment that actually generates free radicals under UV

There’s a clever wrinkle researchers focus on: ordinary UV tanning only kicks in after DNA damage sounds the alarm, whereas Melanotan 1 stimulates the pigment machinery directly (PeptideDeck, 2026). Models still generally show some UV is needed to fully express the pigment, which keeps the peptide-UV interaction an active research question rather than a closed one.

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Full Specifications

Complete quantitative detail for the 10mg vial:

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Where the 10mg Vial Fits in Research

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The GLP1 Peptides Quality Commitment

The COA earns its keep here by confirming the D-Phe⁷ substitution — the D-amino acid that gives MT-1 its stability and selectivity. Verify that, and you know you have genuine Melanotan 1, not a degraded or mis-synthesized peptide.

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Reconstituting the 10mg Vial

Melanotan 1 is light-sensitive — fitting for a pigment peptide — so handle it in subdued light. Warm the sealed vial to room temperature, then run bacteriostatic or sterile water slowly down the inner glass wall rather than onto the powder. Swirl gently until it clears; never shake. Aliquot into single-use portions right away.

Keep the lyophilized powder at -20°C, sealed away from UV light and moisture. Reconstituted, store it cold and dark at 2–8°C, and avoid repeated freeze-thaw cycles. Discard any solution that turns cloudy or discolored.

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MT-1 vs MT-2 vs Native α-MSH

The distinction that matters: both MT-1 and MT-2 stimulate melanogenesis, but Melanotan 1‘s MC1R selectivity is what makes it the tool for isolating pigmentation research from the broader melanocortin pharmacology.

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Melanotan 1 10mg for Sale — Shipping Worldwide

Our research-grade Melanotan 1 10mg ships as HPLC/MS-verified, COA-backed lyophilized vials, meticulously handled and cold-pack protected. We fulfill orders for laboratories and independent researchers across the highest-demand markets:

• 🇺🇸 USA — fast domestic dispatch
• 🇨🇦 Canada — reliable cross-border delivery
• 🇩🇪 Germany (Deutschland) — trusted EU logistics
• 🇫🇷 France — secure European shipping

Deciding to buy Melanotan 1 10mg? It’s the right pick when you want a precise, verified standard quantity for defined melanogenesis or photoprotection work — a clean MC1R-selective peptide with the sequence integrity your data depends on.

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FAQs about Melanotan 1 10mg

1. What is Melanotan 1 10mg? A 10mg vial of Melanotan 1 (afamelanotide), a linear MC1R-selective α-MSH analog, supplied as a lyophilized powder for melanogenesis and photoprotection research.

2. Is Melanotan 1 selective or non-selective? MC1R-selective. It targets the melanocortin-1 receptor with minimal MC3R/MC4R/MC5R activity. The “non-selective across all four receptors” label describes MT-2, not MT-1.

3. Is Melanotan 1 the same as afamelanotide? Yes — identical molecule. Afamelanotide is the pharmaceutical (Scenesse, approved for EPP); this research-grade Melanotan 1 is the same peptide as a powder for laboratory use, not the approved drug.

4. What’s the CAS number for Melanotan 1? 75921-69-6, with molecular formula C₇₈H₁₁₁N₂₁O₁₉ and a molecular weight around 1646.9 g/mol.

5. How does Melanotan 1 produce pigment? By activating MC1R on melanocytes to drive eumelanin — the dark, UV-absorbing, free-radical-scavenging pigment, largely bypassing the DNA-damage step of normal UV tanning.

6. What’s the difference between MT-1 and MT-2? MT-1 is linear and MC1R-selective with a cleaner profile; MT-2 is cyclic and hits MC3R/MC4R too, producing broader systemic effects.

7. Is Melanotan 1 FDA approved? The pharmaceutical form (Scenesse) is FDA-approved for EPP only. This research powder is not the approved product and is not for human, cosmetic, or veterinary use.

8. What is the half-life of Melanotan 1? Roughly 30 minutes after injection, though pigment effects persist for days to weeks since eumelanin accumulation is an ongoing process

9. Does the research on MT-1 have clinical backing? Unusually for a research peptide, yes — the afamelanotide (Scenesse) Phase 3 program provides validated safety and pharmacology data, including the NEJM 2015 EPP trial.

10. How should Melanotan 1 10mg be stored? Lyophilized powder at -20°C, shielded from UV light and moisture; reconstituted solution at 2–8°C, kept dark, freeze-thaw avoided.

11. How do you reconstitute Melanotan 1? Room-temperature vial, bacteriostatic or sterile water down the glass wall, gentle swirl, then aliquot. The handling section above covers it.

12. Where can I buy Melanotan 1 10mg internationally? GLP1 Peptides ships research-grade, COA-verified Melanotan 1 10mg to the USA, Canada, Germany, and France in sealed, cold-pack-protected vials.