Cagrilintide 5mg
$108.00
Cagrilintide 5mg is a high-purity synthetic acylated analog of the naturally occurring glucoregulatory hormone amylin. This long-acting amylin receptor agonist (NNC0165-1875) is specifically synthesized for advanced laboratory research into weight management, glycemic control, and metabolic signaling pathways.
| Property | Specification |
|---|---|
| Compound Name | Cagrilintide (NNC0165-1875) |
| Vial Concentration | 5mg single compound |
| Molecular Formula | C₂₁₂H₃₂₆N₅₀O₆₈ |
| Molecular Weight | 4591.1 g/mol |
| Class | Long-acting acylated amylin analog (AMYR / CTR agonist) |
| Purity Rating | >99% (HPLC & MS verified) |
| Format | White lyophilized powder |
| Solubility | Reconstitutes in bacteriostatic or sterile water |
| Storage | Store at -20°C for long-term stability |
Pure Cagrilintide 5mg for Sale | 99% Pure Long-Acting Amylin Analog (NNC0165-1875)
For decades, obesity research chased a single satiety hormone. Amylin was the quiet second one — co-secreted with insulin, telling the brain you’ve eaten enough — and for a long time it was too short-lived to study well. Cagrilintide changed that. In the Phase 3 REDEFINE 1 trial, cagrilintide monotherapy produced an average 11.8% weight reduction versus 2.3% for placebo over 68 weeks (Pharmacy Times, 2026). Not bad for a hormone that used to disappear from the bloodstream in minutes.
Cagrilintide 5mg (developmental code NNC0165-1875) is a high-purity, long-acting acylated amylin analog — a non-selective agonist of the amylin receptors that also engages calcitonin receptors. The 5mg vial is the standard research quantity: enough for focused single-arm work, dose-finding curves, and precise receptor studies, without committing to a high-yield format you won’t finish. If you’re characterizing amylin signaling rather than running a marathon longitudinal protocol, this is the format sized for you.
At GLP1 Peptides, we supply Cagrilintide 5mg verified to 99%+ purity, backed by a batch-specific Certificate of Analysis (COA), and shipped to laboratories across the USA, Canada, Germany, and France. Here’s everything worth knowing.
Research Use Only. Cagrilintide 5mg is supplied strictly for in-vitro laboratory and analytical research by qualified professionals. It is an investigational compound, not an approved drug, and is not intended for human or veterinary use.
What Is Cagrilintide 5mg?
Cagrilintide is an acylated analog of amylin, the pancreatic hormone that regulates satiety, glucose, and gastric emptying. Native amylin is unstable and short-lived; the acylation — a fatty-acid chain on the peptide backbone — lets it bind albumin in circulation and stay active far longer, which is what makes it a once-weekly research candidate (PMC receptor study, 2025).
The 5mg concentration is the everyday workhorse format — the quantity most labs reach for when the goal is precise, reproducible data rather than sheer volume.
How Cagrilintide works
Cagrilintide reproduces amylin’s three core actions: it reduces food intake through central satiety signaling, inhibits glucagon secretion, and slows gastric emptying. It does this as a non-selective agonist at amylin and calcitonin receptors. A 2025 knockout-mouse study localized its bodyweight effect to brain amylin receptors AMY1 and AMY3 (PMC12270663, 2025).
Here’s the part that keeps drawing researchers back: because amylin works through a different receptor system than GLP-1, the two don’t cancel out — they compound. That’s the whole premise behind studying Cagrilintide alongside GLP-1 receptor agonists, and why its energy-expenditure and adipose-tissue effects are of independent interest.
Why Researchers Buy Cagrilintide 5mg
The standard 5mg format suits precise, focused metabolic research. Here’s where it fits:
| Research Focus | What Cagrilintide 5mg Is Used to Investigate |
|---|---|
| Satiety Signaling | CNS pathways driving long-term reduction in food intake |
| Glycemic Regulation | Inhibition of glucagon secretion and modulation of gastric emptying |
| Synergistic Metabolic Effects | Co-administration with GLP-1 receptor agonists for enhanced weight-loss study |
| Adipose Tissue Homeostasis | Energy-expenditure and lipid-metabolism pathways |
| Dose-Response Studies | Receptor affinity across concentrations in controlled models |
| Single-Arm & Pilot Research | Precise, reproducible data at standard scale |
The GLP1 Peptides Quality Standard
An acylated peptide is only as reliable as its synthesis and documentation. Here’s what backs every 5mg vial:
| Standard | What You Get |
|---|---|
| Verified 99%+ Purity | Every batch confirmed by HPLC and Mass Spectrometry |
| Advanced Lyophilization | Professional freeze-drying protects the acylated sequence for long-term stability |
| Analytical Transparency | A batch-specific Certificate of Analysis (COA) ships with every order |
| Synthesis Precision | Exact acylation and sequencing for consistent receptor affinity in research models |
Technical Product Specifications
| Property | Specification |
|---|---|
| Compound Name | Cagrilintide (NNC0165-1875) |
| Vial Concentration | 5mg single compound |
| Molecular Formula | C₂₁₂H₃₂₆N₅₀O₆₈ |
| Molecular Weight | 4591.1 g/mol |
| Class | Long-acting acylated amylin analog (AMYR / CTR agonist) |
| Purity Rating | >99% (HPLC & MS verified) |
| Format | White lyophilized powder |
| Solubility | Reconstitutes in bacteriostatic or sterile water |
| Storage | Store at -20°C for long-term stability |
How to Reconstitute and Store Cagrilintide 5mg (Laboratory Handling)
The acylated fatty-acid chain makes gentle handling especially important. These are standard in-vitro lab steps — not use directions.
Reconstitution, step by step
| Step | Action |
|---|---|
| 1 | Check your COA and inspect the vial seal, cap, and lyophilized cake |
| 2 | Let the sealed vial reach room temperature to avoid condensation |
| 3 | Add bacteriostatic or sterile water slowly down the inner glass wall — never onto the powder directly |
| 4 | Swirl gently until fully dissolved. Do not shake; agitation stresses acylated peptides |
| 5 | Aliquot into single-use portions to protect the peptide across repeated draws |
Storage at a glance
- Lyophilized powder: store at -20°C, sealed, away from heat, light, and moisture. Stable long-term.
- Reconstituted solution: refrigerate at 2–8°C, protect from light, and avoid repeated freeze-thaw cycles.
- Inspect before every use: discard anything cloudy, discolored, or clumped.
Cold, dark, dry, aliquoted. With an acylated peptide, that gentle discipline is what keeps receptor affinity consistent from vial to bench.
Cagrilintide vs Other Metabolic Research Compounds
Buyers cross-shop Cagrilintide against the broader metabolic field. Here’s how it compares by mechanism.
| Compound | Target | Class | Note |
|---|---|---|---|
| Cagrilintide | Amylin + calcitonin receptors | Long-acting amylin analog | Once-weekly; distinct satiety pathway from GLP-1 |
| Pramlintide | Amylin receptors | Short-acting amylin analog | Same family, but needs frequent dosing vs cagrilintide’s weekly profile |
| Semaglutide | GLP-1 receptor | GLP-1 agonist | Different pathway; paired with cagrilintide in CagriSema research |
| Tirzepatide | GIP + GLP-1 receptors | Dual incretin agonist | Two incretin pathways; separate axis from amylin |
The takeaway: within its own class, Cagrilintide‘s once-weekly, long-acting profile is the leap forward over older analogs like pramlintide — and its non-GLP-1 mechanism is precisely why it’s studied with semaglutide, not against it.
Cagrilintide 5mg for Sale — Availability and International Shipping
Ready to add the standard-format amylin analog to your study? Our research-grade Cagrilintide 5mg ships as HPLC/MS-verified, COA-backed lyophilized vials. We serve laboratories and independent researchers across the highest-demand markets:
- 🇺🇸 USA — fast domestic dispatch
- 🇨🇦 Canada — reliable cross-border delivery
- 🇩🇪 Germany (Deutschland) — trusted EU logistics
- 🇫🇷 France — secure European shipping
Every order arrives sealed, documented, and bench-ready. When you buy Cagrilintide 5mg from GLP1 Peptides, you’re paying for verified identity and full data integrity — the foundation any metabolic study is built on.
FAQs about Cagrilintide 5mg
1. What is Cagrilintide 5mg? It’s a 5mg vial of Cagrilintide (developmental code NNC0165-1875), a long-acting synthetic amylin analog supplied as a lyophilized powder for metabolic research.
2. What does NNC0165-1875 mean? It’s Novo Nordisk’s internal development code for Cagrilintide — the same compound, just referred to by its research designation.
3. How does Cagrilintide work? It mimics amylin — reducing food intake, inhibiting glucagon, and slowing gastric emptying — as a non-selective agonist at amylin and calcitonin receptors, with its weight effect tied to brain receptors AMY1 and AMY3
4. Why choose the 5mg vial over the 10mg? The 5mg is the standard, precise research quantity — ideal for single-arm studies, dose-finding, and receptor work. Step up to 10mg only when you’re running extended longitudinal or high-frequency protocols that need more material.
5. What is the difference between Cagrilintide and semaglutide? Different pathways. Cagrilintide is an amylin analog; semaglutide is a GLP-1 receptor agonist. They target satiety through separate circuits, which is why they’re combined in CagriSema.
6. Is Cagrilintide FDA approved? No. It’s an investigational compound in Novo Nordisk’s Phase 3 program and isn’t approved for any use. This product is supplied for laboratory research only.
7. What is acylation, and why does it matter? Acylation attaches a fatty-acid chain that binds albumin in circulation, extending the molecule’s half-life. That’s what converts short-lived amylin into a once-weekly Cagrilintide research analog.
8. How should Cagrilintide 5mg be stored? Keep the lyophilized powder at -20°C, sealed and away from light and moisture. After reconstitution, refrigerate at 2–8°C, protect from light, and avoid freeze-thaw cycles.
9. How do you reconstitute Cagrilintide 5mg in the lab? Bring the vial to room temperature, add bacteriostatic or sterile water slowly down the glass wall, swirl gently, then aliquot. Full steps are in the how-to table above.
10. Is Cagrilintide the same as pramlintide? Both are amylin analogs, but Cagrilintide is long-acting (once-weekly) while pramlintide is short-acting and needs frequent dosing. That stability is Cagrilintide’s defining advantage.
11. What purity should Cagrilintide be, and how do I verify it? Aim for 99%+ confirmed by HPLC and Mass Spectrometry, documented on a lot-specific COA. Ours ships with exactly that.
12. Where can I buy Cagrilintide 5mg that ships internationally? GLP1 Peptides ships research-grade, COA-verified Cagrilintide 5mg to the USA, Canada, Germany, and France, in sealed lyophilized vials. Availability details are above.
Verified. Documented. Research-ready. Every vial of Cagrilintide 5mg from GLP1 Peptides is HPLC/MS-tested to 99%+ purity and shipped with a batch-specific COA because precise research starts with a precisely made analog.







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