NAD+ 500mg

Original price was: $240.00.Current price is: $219.99.

NAD+ 500mg (Nicotinamide Adenine Dinucleotide) is a high-yield formulation of the essential coenzyme required for cellular energy transfer and systemic metabolic function.

Property Specification
Compound Name Nicotinamide Adenine Dinucleotide (oxidized form)
CAS Number 53-84-9
Vial Concentration 500mg single compound
Molecular Formula C₂₁H₂₇N₇O₁₄P₂
Molecular Weight 663.43 g/mol
Class Redox coenzyme / dinucleotide
Purity Rating >99% (HPLC & MS verified)
Format White lyophilized powder
Solubility Water-soluble
Storage -20°C for long-term stability
Guaranteed Safe Checkout

Premium NAD+ 500mg for Sale | 99% Pure High-Yield Nicotinamide Adenine Dinucleotide

If aging research had a single headline molecule, it would be this one. NAD+ sits at the crossroads of energy metabolism, DNA repair, and longevity signaling — and here’s the fact that made it famous: your NAD+ levels steadily fall as you age, a decline researchers have called an “Achilles’ heel” of aging that drives mitochondrial dysfunction and age-associated disease. Restore it in animal models, and many of those age-related defects can be reversed. That’s why NAD+ has become one of the most in-demand compounds in metabolic and longevity labs worldwide.

This is the NAD+ 500mg high-yield vial — verified 99%+ purity, lyophilized, and sized for serious, repeat-measurement research. If you’re running a study that needs consistent material across many samples or timepoints, this is the format built for you. Let me show you why it’s worth stocking, exactly how to work with it, and where to buy it.

Scope note: research-grade material for in-vitro and laboratory research by qualified professionals only. Not FDA-approved as a drug, not for human or veterinary use, and nothing here is a dosing protocol.


Why NAD+ Sits at the Center of Aging Research

Let’s make the case plainly, because it’s what drives demand. NAD+ (nicotinamide adenine dinucleotide) is the primary electron carrier in cellular energy production — every ATP-generating pathway, from glycolysis to the TCA cycle to oxidative phosphorylation, depends on it. The NAD+/NADH ratio is a master control point linking hundreds of reactions across the cell.

But energy is only half the story. NAD+ is also the essential fuel for three families of enzymes that govern how cells age: sirtuins (SIRT1–7, the longevity-linked deacylases), PARPs (which repair DNA damage), and CD38. As NAD+ declines with age — a decline worsened by obesity and sedentary living — sirtuin and repair activity falter with it. For any lab studying aging, metabolism, or DNA integrity, NAD+ isn’t a niche reagent — it’s foundational.


Why Buy the 500mg High-Yield Format

Here’s the practical buyer’s case. Aging and metabolic studies are long by nature — repeat measurements, multiple arms, dose-response curves. Buy small and you’ll be re-ordering constantly, and every new lot risks introducing batch variation into data you spent weeks building. The NAD+ 500mg vial solves that:

  • One consistent lot across your entire study — batch consistency baked in.
  • Better value at scale — high-yield formats cost less per milligram than repeatedly buying small.
  • Fewer reconstitutions, less handling variability — critical when redox reagents are sensitive.
  • Ready for demanding designs — longitudinal, high-frequency, or multi-arm protocols without running dry mid-experiment.

If you’re running a single quick assay, the 100mg vial is the leaner buy. But for real, sustained research, the 500mg format is the one that keeps your data clean and your reorder cart empty.


The Four Systems Researchers Study

Research Focus What NAD+ 500mg Is Used to Investigate
Mitochondrial Homeostasis NAD+’s role in the electron transport chain and oxidative phosphorylation
Genomic Integrity NAD+ as the essential substrate for PARP enzymes in DNA-damage repair
Sirtuin-Mediated Pathways Activation of SIRT1–SIRT7 and their influence on metabolic health
Systemic Redox Balance Conversion between oxidized (NAD+) and reduced (NADH) states

What the Research Shows

Finding Result Context Source
Age-related decline NAD+ levels fall with age Human & animal; worsened by obesity AHA review
Precursor restoration NAD+ repletion reverses age defects Animal models ScienceDirect review
Human precursor trial NMN raised blood NAD+, well tolerated 250 mg/day, older men PMC, 2022
Enzyme systems Substrate for sirtuins, PARPs, CD38 Metabolism, DNA repair, immunity PMC review
Well-being RCT NAD+ support raised levels & well-being Placebo-controlled medRxiv, 2025

One honest note for accurate research design: much of the strongest human data uses NAD+ precursors (NMN, NR) rather than NAD+ itself, because the intact NAD+ molecule is large and its direct oral bioavailability is debated. That’s exactly the kind of question controlled research exists to explore — and a reason precise, verified material matters.


How to Reconstitute NAD+ 500mg (Step by Step)

You asked for the how-to, so here it is in full. NAD+ is water-soluble, but it’s sensitive to heat and pH, so gentle, cold handling protects your material.

Step What to Do
1 Let the sealed vial reach room temperature to prevent condensation
2 Choose your solvent — sterile or bacteriostatic water is standard; buffer to a neutral pH if your protocol requires it
3 Add the solvent slowly down the inner glass wall, never directly onto the powder
4 Swirl gently until fully dissolved — do not shake, which stresses the coenzyme
5 Prepare it fresh and keep it cold; NAD+ in solution degrades faster than as a dry powder
6 Aliquot into single-use portions immediately to avoid repeated freeze-thaw

How to Store NAD+ 500mg

  • Lyophilized powder: store at -20°C, sealed and away from light and moisture — stable long-term.
  • Reconstituted solution: keep at 2–8°C, use promptly, and protect from light and heat. NAD+ is less stable in solution than dry, so don’t let working stock sit.
  • Freeze-thaw: avoid repeated cycles entirely — aliquot first.
  • Inspect: a fresh solution should be clear; discard anything cloudy, yellowed, or discolored.

Simple habit, big payoff: cold, dark, fresh, and aliquoted keeps a 500mg vial reliable from your first assay to your last.


NAD+ vs NMN vs NR — What’s the Difference?

Buyers cross-shop these constantly, so here’s the honest map.

Compound What It Is Research Role
NAD+ (this product) The active coenzyme itself Direct study of NAD+-dependent reactions and enzymes
NMN Nicotinamide mononucleotide (precursor) Converted to NAD+; most human bioavailability data
NR Nicotinamide riboside (precursor) Another oral NAD+ precursor; well-studied in trials
Nicotinamide Vitamin B3 amide (precursor) Upstream building block of the salvage pathway

The distinction that matters: NAD+ is the destination molecule — the actual coenzyme your enzymes use — while NMN and NR are precursors the body converts into NAD+. For research that needs the active cofactor directly rather than a precursor pathway, NAD+ is the reagent


Why Buy NAD+ From GLP1 Peptides

Standard What It Means for Your Data
99%+ Purity HPLC and Mass Spectrometry verify every batch
Superior Lyophilization Freeze-drying protects the coenzyme from degradation
Batch-Specific COA Full analytical documentation with every order
Consistent Solubility Predictable results across in-vitro and in-vivo work

A redox coenzyme is only as trustworthy as its purity and its paperwork. A verified COA is what separates a reagent you can publish from a variable you have to explain away.


Technical Specifications

Property Specification
Compound Name Nicotinamide Adenine Dinucleotide (oxidized form)
CAS Number 53-84-9
Vial Concentration 500mg single compound
Molecular Formula C₂₁H₂₇N₇O₁₄P₂
Molecular Weight 663.43 g/mol
Class Redox coenzyme / dinucleotide
Purity Rating >99% (HPLC & MS verified)
Format White lyophilized powder
Solubility Water-soluble
Storage -20°C for long-term stability

NAD+ 500mg for Sale — Shipping Worldwide

Our research-grade NAD+ 500mg ships as HPLC/MS-verified, COA-backed lyophilized vials, sealed and bench-ready. We fulfill orders for laboratories and independent researchers across the highest-demand markets:

  • 🇺🇸 USA — fast domestic dispatch
  • 🇨🇦 Canada — reliable cross-border delivery
  • 🇩🇪 Germany (Deutschland) — trusted EU logistics
  • 🇫🇷 France — secure European shipping
  • Global delivery

Ready to stock up for a serious study? When you buy NAD+ 500mg from GLP1 Peptides, you’re getting high-yield, verified coenzyme with the batch consistency long-form research depends on — one lot, one COA, enough material to see your project through. That’s the difference bulk done right makes.


FAQs about NAD+ 500mg

1. What is NAD+ 500mg? A high-yield 500mg vial of NAD+ (nicotinamide adenine dinucleotide, oxidized form), the essential redox coenzyme, supplied as a lyophilized powder for aging, metabolism, and DNA-repair research.

2. Why does NAD+ matter so much in aging research? Because NAD+ levels decline with age, and that decline impairs energy metabolism, sirtuin activity, and DNA repair — making NAD+ a central target in longevity science

3. Why choose the 500mg over the 100mg? Value and consistency. The 500mg high-yield format gives you one lot across a long study, lower cost per milligram, and enough material for multi-arm or repeat-measurement work. The 100mg suits smaller single assays.

4. What’s the difference between NAD+, NMN, and NR? NAD+ is the active coenzyme itself; NMN and NR are precursors the body converts into NAD+. If your research needs the working cofactor directly, NAD+ is the reagent.

5. What enzymes use NAD+? Sirtuins (SIRT1–7), PARPs (DNA repair), and CD38, plus all the redox reactions of energy metabolism

6. How do you reconstitute NAD+ 500mg? Warm the vial, add sterile or bacteriostatic water slowly down the glass wall, swirl gently (never shake), prepare fresh, and aliquot. Full steps are in the how-to table above.

7. How should NAD+ be stored? Powder at -20°C, sealed and dark; reconstituted solution at 2–8°C, used promptly, protected from light and heat, with freeze-thaw avoided — NAD+ is less stable in solution than as powder.

8. Is NAD+ FDA approved? No. It’s a naturally occurring coenzyme supplied here for laboratory research only, not approved as a drug and not for human use.

9. Does oral NAD+ get absorbed well? Direct oral NAD+ bioavailability is debated, which is why much human research uses precursors like NMN and NR. It’s an active research question — and a reason verified, pure material matters.

10. What’s the molecular weight of NAD+? 663.43 g/mol, formula C₂₁H₂₇N₇O₁₄P₂, CAS 53-84-9.

11. Is NAD+ 500mg suitable for in-vivo research? It’s supplied with a consistent solubility profile for both in-vitro and in-vivo research models — always per your own protocol and ethics approvals.

12. Where can I buy NAD+ 500mg internationally? GLP1 Peptides ships research-grade, COA-verified NAD+ 500mg to the USA, Canada, Germany, and France in sealed lyophilized vials. See the shipping section above.

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NAD+ 500mg
NAD+ 500mg

Original price was: $240.00.Current price is: $219.99.

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