SLU-PP-332 5mg for Sale | 99% Pure Pan-ERR Agonist Exercise Mimetic

In late 2023, a molecule from a Saint Louis University lab hit international headlines under a headline-writer’s dream label: “exercise in a pill.” That molecule was SLU-PP-332 — a synthetic pan-agonist of the estrogen-related receptors that, in sedentary mice, switched on much of the same gene program endurance training does, complete with increased treadmill endurance and reduced fat mass (Superpower research guide, 2026). It activates the ERR family with preferential potency at ERRα (EC50 = 98 nM), making it one of the best-characterized pan-ERR agonists available for research.

SLU-PP-332 5mg is the high-purity, research-grade form of that compound — verified 99%+ pure and lyophilized for the lab. I’ll give you the real science here, including an honest look at where the hype has outrun the evidence, plus how to handle it (it’s a small molecule, not a peptide — that matters) and where to buy it.

Scope note: research-grade material for in-vitro and laboratory research by qualified professionals only. Not a drug, dietary supplement, or peptide; not FDA-approved; not for human or veterinary use. Nothing here is a dosing protocol, and all findings described are preclinical.

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What SLU-PP-332 Actually Is (And Isn’t)

Let’s clear up the most common misconception first: SLU-PP-332 is not a peptide. It’s a small synthetic organic molecule — specifically a hydrazide — developed in Thomas Burris’s laboratory at Saint Louis University (Superpower, 2026). The name itself tells the story: SLU for Saint Louis University, PP for Pharmaceutical Probe, 332 for the synthetic iteration number.

Its target is the estrogen-related receptor (ERR) family — ERRα, ERRβ, and ERRγ. And here’s a detail worth knowing: despite the name, these receptors don’t bind estrogen. They’re orphan nuclear receptors, constitutively active transcription factors that govern mitochondrial biogenesis, oxidative phosphorylation, and fatty acid metabolism (Superpower, 2026). SLU-PP-332 was engineered as a research tool to activate all three ERR subtypes at once and study what that activation produces — making it a genuinely novel probe for a receptor family that had long lacked good pharmacological tools.

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The ERR–PGC-1α Mechanism: Exercise Without Exertion

Here’s why the “exercise mimetic” label stuck. When SLU-PP-332 activates the ERRs, it engages the ERR–PGC-1α axis — PGC-1α being the master co-activator that orchestrates the body’s oxidative and thermogenic gene program (Amino Core Research, 2026). That’s the same molecular machinery that endurance exercise recruits.

Downstream, the activated gene program includes targets for fatty acid oxidation, mitochondrial electron-transport-chain components, and oxidative fiber specification (Superpower, 2026). In other words, the transcriptional signature SLU-PP-332 produces in preclinical models resembles the cellular adaptations of sustained aerobic exercise — mitochondrial biogenesis, a shift toward fat-burning metabolism, more oxidative muscle character — but achieved pharmacologically rather than through physical exertion. For researchers studying exercise physiology, that’s a controlled way to probe these pathways without the confounding variables of actual training protocols.

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The Honest Evidence Picture — Read Before You Buy

I’d be doing you a disservice to sell the headline without the footnotes. Every notable finding for SLU-PP-332 — the endurance gains, the fat-mass reduction, the improved insulin sensitivity, the cardiac mitochondrial changes — comes from animal and cell studies. None has been replicated in humans (Superpower, 2026).

More specifically: the media attention and the “exercise in a pill” framing that followed the Burris lab’s 2023 publications have, in the words of one careful analysis, “outpaced the scientific evidence substantially.” The endurance study’s cohorts were very small (around n=6 per group), and there’s no mature human safety data. That doesn’t make the compound uninteresting — quite the opposite; it’s a genuinely novel tool for an under-studied receptor family. But it does make it firmly a research compound, not a proven anything. Any listing that promises human results is selling the hype, not the data.

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Where SLU-PP-332 Fits in Research

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Expanded Technical Specifications

Accuracy note: SLU-PP-332 is a small-molecule hydrazide, not a peptide, and it does not contain chlorine, sulfur, or a triazole ring. If a listing shows a chlorophenyl-triazole-thiobenzene structure or the formula C₁₉H₁₈ClN₃O₂S, that describes a different compound — always confirm identity against the COA.

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The GLP1 Peptides Quality Standard

Because SLU-PP-332 is easily confused with unrelated triazole compounds in careless catalogs, that COA matters — it confirms you have the genuine hydrazide (CAS 303760-60-3), not a look-alike.

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How to Handle SLU-PP-332 in the Lab

This is where SLU-PP-332 differs from every peptide on this site — it’s a small molecule, so it’s handled like one, not reconstituted in bacteriostatic water.

• Making a stock solution (in-vitro): SLU-PP-332 is poorly water-soluble. Dissolve it in DMSO to make a concentrated stock (commonly in the 10–50 mM range), then dilute into your assay medium so the final DMSO concentration stays low enough not to affect your cells.
• Warm and measure: let the vial reach room temperature first, and weigh or aliquot precisely — small-molecule work lives and dies on accurate concentration.
• Protect the stock: keep DMSO stocks tightly sealed (DMSO is hygroscopic and absorbs water from the air), aliquoted, and frozen.

How to Store SLU-PP-332 5mg

• Powder: -20°C, sealed, dark, and dry — stable long-term.
• DMSO stock: aliquot and store frozen; avoid repeated freeze-thaw, and minimize air exposure.
• Inspect: discard any stock that shows precipitation or discoloration.

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SLU-PP-332 vs Other Exercise Mimetics

The clean framing: SLU-PP-332 hits the ERR–PGC-1α axis directly, a distinct entry point from the AMPK route (AICAR, MOTS-c) or the PPARδ route (GW501516). For researchers mapping how different molecular switches reproduce the exercise response, it’s the ERR-family tool.

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SLU-PP-332 5mg for Sale — Shipping Worldwide

Our research-grade SLU-PP-332 5mg ships as HPLC/MS-verified, COA-backed vials, sealed and bench-ready. We fulfill orders for laboratories and independent researchers across the highest-demand markets:

• 🇺🇸 USA — fast domestic dispatch
• 🇨🇦 Canada — reliable cross-border delivery
• 🇩🇪 Germany (Deutschland) — trusted EU logistics
• 🇫🇷 France — secure European shipping

When you buy SLU-PP-332 5mg from GLP1 Peptides, you get a verified pan-ERR agonist with confirmed molecular identity — the assurance that you’re studying the genuine Burris-lab compound, not a mislabeled substitute.

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FAQs about SLU-PP-332 5mg

1. What is SLU-PP-332 5mg? A 5mg vial of SLU-PP-332, a synthetic small-molecule pan-agonist of the estrogen-related receptors (ERRα/β/γ), supplied for metabolic, mitochondrial, and exercise-physiology research.

2. Is SLU-PP-332 a peptide? No — it’s a small organic molecule (a hydrazide), not a peptide. That distinction matters for how you handle it: it’s dissolved in DMSO, not reconstituted in water like a peptide.

3. Why is it called an “exercise mimetic”? Because activating the ERRs engages the ERR–PGC-1α axis, reproducing much of the gene program that endurance exercise activates — mitochondrial biogenesis, fat oxidation, oxidative muscle character — in preclinical models).

4. Do the estrogen-related receptors bind estrogen? No — despite the name, ERRs are orphan nuclear receptors that don’t bind estrogen. They’re constitutively active regulators of energy metabolism.

5. Is there human data on SLU-PP-332? None. Every finding is from animal or cell studies, and the “exercise in a pill” media framing has run well ahead of the actual evidence.

6. Who developed SLU-PP-332? Thomas Burris and Cyrielle Billon’s lab at Saint Louis University — the “SLU” in the name — first characterized it in 2023.

7. How do I prepare SLU-PP-332 for research? Dissolve it in DMSO to make a concentrated stock, then dilute into your assay medium keeping final DMSO low. It’s poorly water-soluble, so it isn’t handled like a peptide. See the handling section above.

8. How should SLU-PP-332 be stored? Powder at -20°C, sealed and dark; DMSO stocks aliquoted, frozen, and kept from air (DMSO absorbs moisture). Avoid freeze-thaw.

9. Is SLU-PP-332 FDA approved? No — it’s an early-stage research compound with no approval and no mature human safety data.

10. Is SLU-PP-332 banned in sport? Exercise mimetics are under anti-doping scrutiny, and as a metabolic modulator it may fall under WADA’s S4 category — athletes under testing programs should verify current status.

11. What purity should SLU-PP-332 be? Aim for 99%+ verified by HPLC and Mass Spectrometry, with a lot-specific COA confirming the correct hydrazide identity (CAS 303760-60-3). Ours ships with that.

12. Where can I buy SLU-PP-332 5mg internationally? GLP1 Peptides ships research-grade, COA-verified SLU-PP-332 5mg to the USA, Canada, Germany, and France in sealed vials. See the shipping section above.